Pulmonology Research

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We see children in our specialty clinics day in and day out living with cystic fibrosis as well as high-risk asthma, primary ciliary dyskinesia and chronic ventilation. Our researchers work to find the best therapies and cures for children with these conditions.

Pulmonology research patient receiving a cystic fibrosis test

Our Research

  • Host-pathogen interactions in special populations with underlying chronic lung disease
  • Immuno- and patho-biology of allergic hosts during respiratory infections (influenza virus and pneumococci), the role of antimicrobial peptides at the air-lung interphase and eosinophil development and function in health and disease
  • Duchenne muscular dystrophy, cystic fibrosis (CF) and asthma
  • Basic and translational CF studies:
    • Characterization of an inhibitory protein complex for CF therapy
    • Characterization of novel CF mutations
    • Roles of CF transmembrane conductance regulator-containing protein complexes in fluid secretion and inflammatory responses in gastrointestinal systems
  • Proximity to local CF care center as a predictor of overall access to health care and positive health outcomes
  • Sleep disturbances and obesity
  • Screening tools and management for obstructive sleep apnea (OSA) and management for obstructive sleep apnea
  • Primary ciliary dyskinesia, CF quality improvement and aerodigestive diseases

Clinical Trials

If you are interested in participating in a pulmonology clinical trial, please view our list of current and active trials.

Recent Publications

Related Articles

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Airway Microbiome in Asthma

Le Bonheur researchers review the impact of the microbiome on asthma development, severity in the fi...

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