Tuberous Sclerosis Complex

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We are leaders in the clinical care and research of Tuberous Sclerosis Complex (TSC), a genetic disorder that causes tumor growth in organs throughout the body.

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Comprehensive clinic

Designated by the national Tuberous Sclerosis Alliance, our multidisciplinary clinic gives patients access to pediatric experts in cardiology, neurology, pulmonology and urology in one setting -- from childhood into adulthood.

Our advanced diagnostic tools also help families and the medical team make the best decisions for each patient.

Our TSC clinic is led by Pediatric Nephrologist John Bissler, MD. Neurologist Jim Wheless, MD, serves as the co-director and Thomas Yohannan, MD serves as the clinic's pediatric cardiologist. Both Dr. Bissler and Dr. Wheless serve as members of the Tuberous Sclerosis Alliance’s Professional Advisory Board. Pediatric Neurologist and Neurodevelopmental Specialist Tanjala Gipson, MD, leads Le Bonheur's TSC-Associated Neuropsychiatric Disorders Clinic.

The clinic also hosts educational programs for families and helps ensure all receive the best care possible. Through the Tuberous Sclerosis Alliance, we are able to provide families with information to understand TSC and better communicate with their child’s school and teachers.

Program Co-director Wheless explains how seeking treatment at a TSC center of excellence can improve a patient's outcome.

Tuberous Sclerosis: Building a complex program from Le Bonheur Children's Hospital on Vimeo.

Expanding research

The physician researchers who care for TSC patients are also involved in studies to better understand the disease and develop innovative treatment options.

Our physicians are leaders in the treatment and research of TSC. They have shared their knowledge at the International Research Conference on TSC and Related Disorders hosted by The Rothberg Institute for Childhood Diseases and the Tuberous Sclerosis Alliance.

Facebook Live

Le Bonheur physicians Sarah Weatherspoon, MD, John Bissler, MD, and Chester Brown, MD, PhD, sat down with Le Bonheur parent Brittany Schwaigert. Her son, Greyson, has TSC.

Visiting Le Bonheur

Patients and families who come to the TSC Center of Excellence at Le Bonheur will work with a nurse coordinator to schedule their visit.

Traveling to Memphis

For more information

For more information about our TSC Clinic, call 901-287-7492.